Depression is different for everyone whom it affects. While 17.3 million adults in the United States experience at least one major depressive episode in a year, the risk of recurrence varies. A 2012 study in Psychological Medicine found that the risk of recurrence of major depressive disorder was 13.2% after 5 years, 23.2% after 10 years, and 42.0% after 20 years.

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